|
|
|
|
|
Click Here to return To Results
|
|
|
|
There was minimal change in the degree of pain in the lidocaine-only and control groups during and after the treatment period. In the methylprednisolone-lidocaine group, the intensity and area of pain decreased, and the use of the nonsteroi dal antiinflammatory drug diclofenac declined by more than 70 percent four weeks after the end of treatment. No complications related to intrathecal methylpredniosolone were observed. Before treatment, the concentrations of interleukin-8 in the cerebros pinal fluid were inversely related to the duration of neuralgia in all the patients (r=-0.49, P<0.001). In the patients who received methylprednisolone, interleukin-8 concentrations decreased by 50 percent, and this decrease correlated with the duration of neuralgia and with the extent of global pain relief (P<0.001 for both comparisons). The results of this trial indicate that the intrathecal administration of methylprednisolone is an effective treatment for postherpetic neuralgia. |
|
(click to filter results - removes previous filter)
herpes zoster
intrathecal steroid
neuralgia
neuralgia,intercostal
neuralgia,treatment of
pain
pain,management of chronic
post herpetic neuralgia
steroid
steroid therapy,CNS treatment and complications with
treatment of neurologic disorder
|
Click Here to return To Results
|
|